Systematic Yersinia enterocolitica in an iron overloaded and immunocompromised thalassemic patient

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Infection with Yersinia enterocolitica in patients with iron overload.

Yersinia enterocolitica commonly causes fever and mild gastroenteritis' but occasionally causes severe illness, particularly in patients with iron overload in whom its virulence is enhanced.2 Desferrioxamine used therapeutically may potentiate the growth of yersinia, which uses desferrioxamine as a siderophore to chelate iron.3 We describe three patients with transfusional haemosiderosis and in...

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Yersinia enterocolitica.

Characteristics of the disease Infectious dose is 10–100 organisms Incubation period is 1⁄2–4 (usually 1–3) days; up to a week for S. dysenteriae 1 Illness: diarrhea with fever and nausea; sometimes toxemia, vomiting, cramps, and tenesmus; dysentery—blood and mucus in stools; may cause hemolytic uremic syndrome; most severe in infants; mild and asymptomatic infections occur Duration: 4–7 days; ...

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Yersinia enterocolitica Septicemia After Chitterling Ingestion in a Pediatric Patient With Iron Overload Disease

Yersinia enterocolitica is a gram-negative cocobacillus causing a range of illness from self-limited enteritis to invasive disease, including septicemia. It is a particularly virulent pathogen in patients with underlying hemoglobinopathies who are predisposed to iron overload. A substantial risk factor for disease in children and infants is exposure to the household preparation of chitterlings....

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Septicaemia due to Yersinia enterocolitica after oral overdoses of iron.

Septicaemia occurred after accidental oral overdoses of iron in two previously healthy children. Yersinia enterocolitica serotype 0:3 was recovered from blood and stool cultures in both patients. Enhanced growth of Y enterocolitica in the intestine combined with damage of intestinal mucosa may have been of major importance for the development of generalised infection in these cases. Iron and th...

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ژورنال

عنوان ژورنال: Microbiologia Medica

سال: 2017

ISSN: 2280-6423

DOI: 10.4081/mm.2017.6873